Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Diethyl Ether | HCID 3283 | — |
| Reactant | 3,4-Dimethoxyphenethyl bromide | HCID 11470602 | — |
| Reactant | HCID 19803475 | HCID 19803475 | — |
| Solvent | Dichloromethane methanol | HCID 21226129 | — |
| Product | HCID 19803857 | HCID 19803857 | — |
Reaction Steps
A mixture of 1.1 g (0.0035 mol) of 3-[(pyridin-3-yl)methyl]-7,8-dimethoxy-1,3-dihydro-2H-3-benzazepin-2-one and 2-(3,4-dimethoxyphenyl)-ethyl bromide is heated to 110° C. for 6 hours. After cooling, the reaction mixture is dissolved in a little methanol/ methylene chloride and added dropwize to 200 ml of diethylether, with vigorous stirring. The precipitate obtained is suction filtered and dried. Yield: 1.6 g (80% of theory), Melting point: 147°-150° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US05175157 |
|---|
| Source dataset | uspto-grants-1992_12 |
|---|
| ORD ID | ord-16f2de8816f34fa290e98c1638caf86c |
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| Source note | uspto-grants-1992_12 |
|---|
