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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1682061Generated: November 4, 2026

3-[(piperidin-3-yl)-methyl]-7,8-dimethoxy1,3,4,5-tetrahydro-2H-3-benzazepin-2-one → 3-[(N-(2-(4-Methoxy-benzo[b]thien-3-yl)-ethyl)-piperidin-3-yl)-methyl]-7,8-dimethoxy-2-oxo-1,3,4,5-tetrahydro-2H-3-benzazepine-hydrochloride

https://huagongshe.com/reaction/1682061

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-[(piperidin-3-yl)-methyl]-7,8-dimethoxy1,3,4,5-tetrahydro-2H-3-benzazepin-2-oneHCID 19803841—
Reactant3-(2-Chloroethyl)-4-methoxy-benzo[b]thiopheneHCID 19804109—
Product3-[(N-(2-(4-Methoxy-benzo[b]thien-3-yl)-ethyl)-piperidin-3-yl)-methyl]-7,8-dimethoxy-2-oxo-1,3,4,5-tetrahydro-2H-3-benzazepine-hydrochlorideHCID 67917724—

Reaction Steps

Prepared from 3-[(piperidin-3-yl)-methyl]-7,8-dimethoxy-2-oxo-1,3,4,5-tetrahydro-2H-3-benzazepine and 3-(2-chloroethyl)-4-methoxy-benzo[b]thiophene analogously to Example 1.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05175157
Source datasetuspto-grants-1992_12
ORD IDord-12ca4ea9486f4eb8b7c6aae6d2533a04
Source noteuspto-grants-1992_12