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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1682071Generated: November 2, 2026

7,8-dimethoxy-2,3,4,5-tetrahydro-1H-3-benzazepin-2-one → 3-[(N-(3-(3-Methyl-phenoxy)-propyl)-hexahydro-azepin-3-yl)methyl]-7,8-dimethoxy-2-oxo-1,3,4,5-tetrahydro-2H-3-benzazepinehydrochloride

https://huagongshe.com/reaction/1682071

Reaction equation

Participants

RoleNameHCIDCharge
Reactant7,8-dimethoxy-2,3,4,5-tetrahydro-1H-3-benzazepin-2-oneHCID 11401769—
ReactantN-[3-(3-methyl-phenoxy)-propyl]-3-chloromethylhexahydro-azepineHCID 19803932—
Product3-[(N-(3-(3-Methyl-phenoxy)-propyl)-hexahydro-azepin-3-yl)methyl]-7,8-dimethoxy-2-oxo-1,3,4,5-tetrahydro-2H-3-benzazepinehydrochlorideHCID 67918223—

Reaction Steps

Prepared from 7,8-dimethoxy-2-oxo-1,3,4,5-tetrahydro-2H-3-benzazepine and N-[3-(3-methyl-phenoxy)-propyl]-3-chloromethylhexahydro-azepine analogously to Example 2.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05175157
Source datasetuspto-grants-1992_12
ORD IDord-0a901e3300ce4e45a724f8b1a8db9b3a
Source noteuspto-grants-1992_12