反应详情

In 50 ml of EtOH was dissolved 2.3 g (0.01 mole) of 1-methylthio-1-(3-pyridylmethyl)amino-2-nitroethylene with heating and, then, a solution of 1.2 g (0.015 mole) of 40% aqueous methylamine in 10 ml of EtOH was added dropwise over a period of 30 minutes while refluxing. The mixture was further refluxed for 2 hours, after which it was concentrated. The crystals were collected by filtration and recrystallized from acetonitrile to give 1.6 g of the title compound as white prisms.

1. temperaturewith heating
2. temperaturewhile refluxing
3. temperatureThe mixture was further refluxed for 2 hours
4. concentrationafter which it was concentrated
5. filtrationThe crystals were collected by filtration
6. customrecrystallized from acetonitrile