HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 1-Ethyl (3E)-2-amino-4-methyl-5-phosphono-3-pentenoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Ethanol | HCID 702 | — |
| Reactant | CGP 37849 | HCID 5950212 | — |
| Product | 1-Ethyl (3E)-2-amino-4-methyl-5-phosphono-3-pentenoate | HCID 6372334 | — |
Reaction Steps
2.0 g of E-2-amino-4-methyl-5-phosphono-3-pentenoic acid are placed in 50 ml of ethanol and the whole is saturated with hydrogen chloride gas for 21/2 hours at 50°. After concentration, the residue is dissolved in 20 ml of ethanol, 20 ml of propylene oxide are added and the precipitate is filtered off. Recrystallisation from water/ethanol (1:3) yields E-2-amino-4-methyl-5-phosphono-3-pentenoic acid ethyl ester, m.p. 193°-194°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05175344 |
| Source dataset | uspto-grants-1992_12 |
| ORD ID | ord-94eccedb415d4888957a1fda5f40a3a0 |
| Source note | uspto-grants-1992_12 |