Hydrochloric Acid → HCID 19804964, compound

Participants

Reaction Steps

E-2-formylamino-5-diethylphosphono-5-methyl-3-pentenoic acid ethyl ester is hydrolysed with 4.35 N hydrochloric acid in the manner described in Example 11. E-2-amino-5-methyl-5-phosphono-3-pentenoic acid is isolated in the form of an amorphous white solid mass. 1H-NMR (D2O) 1.05 (dd, 3H, CH3); 2.45 (m, 1H, C(5)-H); 4.33 (d, 2H, C(2)-H); 5.5 and 5.9 (2m, 2H, C(3)-H and C(4)-H).

Provenance & Evidence