Ethanol → 4-(4-(Pyridin-3-yl)-1H-imidazol-1-yl)butan-1-amine

HRID 1682429Notes

Reaction equation

HRID 1682429 reaction equation
[N:1]1[CH:6]=[CH:5][CH:4]=[C:3]([C:7]2[N:8]=[CH:9][N:10]([CH:12](CC)[CH2:13]N3C(=O)C4C(=CC=CC=4)C3=O)[CH:11]=2)[CH:2]=1.O.[NH2:28]N.[CH2:30](O)[CH3:31]>>[CH:5]1[CH:6]=[N:1][CH:2]=[C:3]([C:7]2[N:8]=[CH:9][N:10]([CH2:12][CH2:13][CH2:30][CH2:31][NH2:28])[CH:11]=2)[CH:4]=1

Participants

4

Reactant 3

HCID 702EthanolHCID 24654Hydrazine hydrate (1:1)HCID 186948072-(4-(3-pyridinyl)-1H-imidazol-1-yl)-butyl-1H-iso-indol-1,3(2H)-dione

Product 1

HCID 110421604-(4-(Pyridin-3-yl)-1H-imidazol-1-yl)butan-1-amine

Procedure

Using the procedure of Stage B of Example 1, 1.66 g of the product of Stage A and 0.46 ml of hydrazine hydrate in 30 ml of ethanol were reacted to obtain 936 mag of the desired product which was used as is for the synthesis.

Workup

  1. customwere reacted

Sources & evidence

ORD record
ord-deef02374e4b4015adfe8eaec2a1920c
Source dataset
uspto-grants-1997_06
Patent number
US05635485

Reaction notes

Loading…