Hydrochloric Acid → HCID 67562209, compound

HRID 1682995Notes

Reaction equation

HRID 1682995 reaction equation
C(OC([N:8]1[CH2:13][CH2:12][C:11]([C:17]2[CH:26]=[CH:25][C:24]3[C:19](=[CH:20][CH:21]=[CH:22][CH:23]=3)[CH:18]=2)([C:14]([NH2:16])=[O:15])[CH2:10][CH2:9]1)=O)(C)(C)C.[ClH:27].O1CCOCC1>>[ClH:27].[CH:18]1[C:19]2[C:24](=[CH:23][CH:22]=[CH:21][CH:20]=2)[CH:25]=[CH:26][C:17]=1[C:11]1([C:14]([NH2:16])=[O:15])[CH2:10][CH2:9][NH:8][CH2:13][CH2:12]1

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 312751,4-DioxaneHCID 54050792HCID 54050792, compound

Product 1

HCID 67562209HCID 67562209, compound

Procedure

Prepare by the method of example 20.10 using 1-tert-butoxycarbonyl-4-(naphth-2-yl)-piperidine-4-carboxylic acid amide (3 mmol) and HCl in dioxane (40 mmol, 4N) to give the title compound.

Sources & evidence

ORD record
ord-296b3e94e8244d71815db0e47cbf9330
Source dataset
uspto-grants-1997_06
Patent number
US05635510

Reaction notes

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