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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1682997Generated: November 1, 2026

2-(Pyridin-4-yl)acetonitrile → 1-Boc-4-cyano-4-(4-pyridinyl)-piperidine

https://huagongshe.com/reaction/1682997

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(Pyridin-4-yl)acetonitrileHCID 4112085—
ReactantN-BOC-N,N-Bis(2-chloroethyl)amineHCID 11230235—
Product1-Boc-4-cyano-4-(4-pyridinyl)-piperidineHCID 53944325—

Reaction Steps

Prepare by the method of example 30.2 using 4-pyridylacetonitrile (10 mmol) and 2-chloro-N-(2-chloroethyl)-N-tert-butoxycarbonyl-ethanamine (11 mmol). Purify to give the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05635510
Source datasetuspto-grants-1997_06
ORD IDord-3c6bfe251550441f9c604d34b3b642db
Source noteuspto-grants-1997_06