Hydrochloric Acid → HCID 67562162, compound

HRID 1682998Notes

Reaction equation

HRID 1682998 reaction equation
C(OC([N:8]1[CH2:13][CH2:12][C:11]([C:20]#[N:21])([C:14]2[CH:19]=[CH:18][N:17]=[CH:16][CH:15]=2)[CH2:10][CH2:9]1)=O)(C)(C)C.[ClH:22].O1CCOCC1>>[ClH:22].[C:20]([C:11]1([C:14]2[CH:19]=[CH:18][N:17]=[CH:16][CH:15]=2)[CH2:12][CH2:13][NH:8][CH2:9][CH2:10]1)#[N:21]

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 312751,4-DioxaneHCID 539443251-Boc-4-cyano-4-(4-pyridinyl)-piperidine

Product 1

HCID 67562162HCID 67562162, compound

Procedure

Prepare by the method of example 30.3 using 1-tert-butoxycarbonyl-4-cyano-4-(pyridin-4-yl)-piperidine (3 mmol) and HCl in dioxane (40 mmol, 4N). Concentrate the solvent in vacuo and dry under high vacuum to give the title compound.

Workup

  1. concentrationConcentrate the solvent in vacuo
  2. customdry under high vacuum

Sources & evidence

ORD record
ord-04df1e0b19b54b618ce5e461f2ef70ca
Source dataset
uspto-grants-1997_06
Patent number
US05635510

Reaction notes

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