Hydrochloric Acid → 4-(Pyridin-4-yl)-piperidine-4-carboxylic acid amide hydrochloride

HRID 1683000Notes

Reaction equation

HRID 1683000 reaction equation
C(OC([N:8]1[CH2:13][CH2:12][C:11]([C:17]2[CH:22]=[CH:21][N:20]=[CH:19][CH:18]=2)([C:14]([NH2:16])=[O:15])[CH2:10][CH2:9]1)=O)(C)(C)C.[ClH:23].O1CCOCC1>>[ClH:23].[N:20]1[CH:21]=[CH:22][C:17]([C:11]2([C:14]([NH2:16])=[O:15])[CH2:12][CH2:13][NH:8][CH2:9][CH2:10]2)=[CH:18][CH:19]=1

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 312751,4-DioxaneHCID 54235505HCID 54235505, compound

Product 1

HCID 675621254-(Pyridin-4-yl)-piperidine-4-carboxylic acid amide hydrochloride

Procedure

Prepare by the method of example 20.10 using 1-tert-butoxycarbonyl-4-(pyridin-4-yl)-piperidine-4-carboxylic acid amide (3 mmol) and HCl in dioxane (40 mmol, 4N) to give the title compound.

Sources & evidence

ORD record
ord-b5a978df9ef94362971b721150ca14f0
Source dataset
uspto-grants-1997_06
Patent number
US05635510

Reaction notes

Loading…