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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1683002Generated: November 1, 2026

3-Pyridineacetonitrile → tert-Butyl 4-cyano-4-(pyridin-3-yl)piperidine-1-carboxylate

https://huagongshe.com/reaction/1683002

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-PyridineacetonitrileHCID 80923—
ReactantN-BOC-N,N-Bis(2-chloroethyl)amineHCID 11230235—
Producttert-Butyl 4-cyano-4-(pyridin-3-yl)piperidine-1-carboxylateHCID 53793625—

Reaction Steps

Prepare by the method of example 30.2 using 3-pyridylacetonitrile (10 mmol) and 2-chloro-N-(2-chloroethyl)-N-tert-butoxycarbonyl-ethanamine (11 mmol).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05635510
Source datasetuspto-grants-1997_06
ORD IDord-4f2b25ac94824791a82b8635a8f96cde
Source noteuspto-grants-1997_06