HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 4-Cyano-4-(pyridin-3-yl)-piperidine hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 1,4-Dioxane | HCID 31275 | — |
| Reactant | tert-Butyl 4-cyano-4-(pyridin-3-yl)piperidine-1-carboxylate | HCID 53793625 | — |
| Product | 4-Cyano-4-(pyridin-3-yl)-piperidine hydrochloride | HCID 53363272 | — |
Reaction Steps
Prepare by the method of example 30.3 using 1-tert-butoxycarbonyl-4-cyano-4-(pyridin-3-yl)-piperidine (3 mmol) and HCl in dioxane (40 mmol, 4N). Concentrate the solvent in vacuo and dry under high vacuum to give the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05635510 |
| Source dataset | uspto-grants-1997_06 |
| ORD ID | ord-2520bb6dcbc7418eaaee1123017f9c00 |
| Source note | uspto-grants-1997_06 |