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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1683027Generated: November 3, 2026

1-(4-Tert-butylphenyl)-2-chloroethan-1-one → 2-[3-(3,4-Dichloro-phenyl)-1-(4-tert-butyl-phenacyl)-pyrrolidin-3-yl]-ethanol

https://huagongshe.com/reaction/1683027

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(4-Tert-butylphenyl)-2-chloroethan-1-oneHCID 229661—
Reactant2-(3-(3,4-Dichlorophenyl)pyrrolidin-3-yl)ethanolHCID 18464427—
Product2-[3-(3,4-Dichloro-phenyl)-1-(4-tert-butyl-phenacyl)-pyrrolidin-3-yl]-ethanolHCID 54016703—

Reaction Steps

Prepare by the method of example 3.1 using 2-[3-(3,4-dichloro-phenyl)-pyrrolidin-3-yl]-ethanol (2 mmol) and 4-tert-butyl-phenacyl chloride (2 mmol). Chromatograph on silica gel to give the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05635510
Source datasetuspto-grants-1997_06
ORD IDord-21b0d107a7b84751a45047e1342ce93e
Source noteuspto-grants-1997_06