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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1683075Generated: October 27, 2026

3-Isopropoxybenzoyl chloride → 2-[3-(4-Trifluoromethyl-phenyl)-1-(3-isopropoxy-benzoyl)-pyrrolidin-3-yl]-ethanol

https://huagongshe.com/reaction/1683075

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Isopropoxybenzoyl chlorideHCID 4769462—
Reactant2-[3-(4-Trifluoromethyl-phenyl)-pyrrolidin-3-yl]-ethanolHCID 18333487—
Product2-[3-(4-Trifluoromethyl-phenyl)-1-(3-isopropoxy-benzoyl)-pyrrolidin-3-yl]-ethanolHCID 54513905—

Reaction Steps

Prepare by the method of example 3.1 using 2-[3-(4-trifluoromethyl-phenyl)-pyrrolidin-3-yl]-ethanol (23 mmol) and 3-isopropoxy-benzoyl chloride (23 mmol). Chromatograph on silica gel to give the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05635510
Source datasetuspto-grants-1997_06
ORD IDord-265f07697c9047cd8cbbbfc6e5727e92
Source noteuspto-grants-1997_06