Hydrochloric Acid → HCID 67561003, compound

HRID 1683079Notes

Reaction equation

HRID 1683079 reaction equation
C(OC([N:8]1[CH2:13][CH2:12][C:11]([C:19]#[N:20])([C:14]2[S:15][CH:16]=[CH:17][CH:18]=2)[CH2:10][CH2:9]1)=O)(C)(C)C.[ClH:21].O1CCOCC1>>[ClH:21].[C:19]([C:11]1([C:14]2[S:15][CH:16]=[CH:17][CH:18]=2)[CH2:12][CH2:13][NH:8][CH2:9][CH2:10]1)#[N:20]

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 312751,4-DioxaneHCID 54508573HCID 54508573, compound

Product 1

HCID 67561003HCID 67561003, compound

Procedure

Prepare by the method of example 30.3 using 1-tert-butoxycarbonyl-4-cyano-4-(thiophen-2-yl)-piperidine (3 mmol) and HCl in dioxane (4N, 40 mmol). Concentrate the solvent in vacuo and dry under high vacuum to give the title compound.

Workup

  1. concentrationConcentrate the solvent in vacuo
  2. customdry under high vacuum

Sources & evidence

ORD record
ord-587daab604bf4bf8b868b3ddd982ce88
Source dataset
uspto-grants-1997_06
Patent number
US05635510

Reaction notes

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