HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sulfuric Acid → 3-Tetrahydropyranyloxyethyl-3-(3,4-dichlorophenyl)pyrrolidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sulfuric Acid | HCID 1118 | — |
| Reactant | 4-(2-Tetrahydropyranyloxyethyl)-4-(3,4-dichlorophenyl)-2-pyrrolidone | HCID 21197671 | — |
| Product | 3-Tetrahydropyranyloxyethyl-3-(3,4-dichlorophenyl)pyrrolidine | HCID 21197687 | — |
Reaction Steps
Prepare according to the method of example 1.3.2 using 4-(3,4-dichloro-phenyl)-4-[2-(tetrahydro-pyran-2-yloxy)ethyl ]-pyrrolidin-2-one (as prepared in example 11.3) (3 mmol), LiA1H4 (18 mmol) H2SO4 (99.999%) (9 mmol). Purify to give the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05635510 |
| Source dataset | uspto-grants-1997_06 |
| ORD ID | ord-5880b5e7d2ff4bc9aac696a5251fb9fe |
| Source note | uspto-grants-1997_06 |