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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1683284Generated: October 31, 2026

HCID 19042891, compound → HCID 19042902, compound

https://huagongshe.com/reaction/1683284

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 19042891HCID 19042891—
SolventSodium HydroxideHCID 14798—
ProductHCID 19042902HCID 19042902—

Reaction Steps

Ethyl 5-(4-methylphenoxy)indole-2-carboxylate (1.0 g, 3.39 mmol) was hydrolysed in methanolic NaOH (3.2M, 6.0 mL) at reflux, for 1 hr. After work-up the product: 5-(4-methylphenoxy)indole-2-carboxylic acid was obtained as an almost white solid, 0.92 g (ca 100%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05637593
Source datasetuspto-grants-1997_06
ORD IDord-92eecd3873ef4003997b0dcd826492b7
Source noteuspto-grants-1997_06