2,3-Dimethoxy-3-oxopropanoate → HCID 178501832, compound

HRID 1683304Notes

Reaction equation

HRID 1683304 reaction equation
[CH3:1][O:2][CH:3]([C:8]([O-:10])=O)[C:4]([O:6][CH3:7])=[O:5].[NH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][N:20]=[C:21]([NH:30][C:31](=[O:37])[O:32][C:33]([CH3:36])([CH3:35])[CH3:34])[NH:22][C:23](=[O:29])[O:24][C:25]([CH3:28])([CH3:27])[CH3:26]>>[CH3:35][C:33]([CH3:36])([O:32][C:31]([NH:30][C:21]([NH:20][CH2:19][CH2:18][CH2:17][CH2:16][CH2:15][CH2:14][CH2:13][CH2:12][NH:11][C:8](=[O:10])[CH:3]([O:2][CH3:1])[C:4]([O:6][CH3:7])=[O:5])=[N:22][C:23]([O:24][C:25]([CH3:26])([CH3:27])[CH3:28])=[O:29])=[O:37])[CH3:34]

Participants

3

Reactant 2

HCID 229990802,3-Dimethoxy-3-oxopropanoateHCID 25214054Bis(1,1-dimethylethyl) [[(8-aminooctyl)imino]methylene]biscarbamate

Product 1

HCID 178501832HCID 178501832, compoundYield 95%

Procedure

By following a procedure analogous to the method of Preparation 18, using 3.5 g (23.65.10-3 mol) of methyl 2-methoxypropanedioate and 7 g (18.1.10-3 mol) of bis(1,1-dimethylethyl) [[(8-aminooctyl)imino]methylene]biscarbamate as the starting materials, 8.6 g (yield=95%) of the expected product are obtained in the form of a yellow oil.

Workup

  1. customto the method of Preparation 18

Sources & evidence

ORD record
ord-52ee23ce7f68449cba206de89f0aeb7e
Source dataset
uspto-grants-1997_06
Patent number
US05637613

Reaction notes

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