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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 168351Generated: October 31, 2026

Hydrochloric Acid → N4-[2-(5-chloro-2-fluoro-phenyl)-[1,8]naphthyridin-4-yl]-pyrimidine-2,4-diamine

https://huagongshe.com/reaction/168351

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
Reactant1,4-DioxaneHCID 31275—
Reactant{4-[2-(5-Chloro-2-fluoro-phenyl)-[1,8]naphthyridin-4-ylamino]-pyrimidin-2-yl}-carbamic acid tert-butyl esterHCID 53372717—
ProductN4-[2-(5-chloro-2-fluoro-phenyl)-[1,8]naphthyridin-4-yl]-pyrimidine-2,4-diamineHCID 53372718—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (9/10)
ORD IDord-8eeff0af827749a9b7de1755135ff796
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (9/10)