Formaldehyde → HCID 19040835, compound

HRID 1683722Notes

Reaction equation

HRID 1683722 reaction equation
[CH3:1][C:2]1[N:3]=[C:4]2[N:8]([CH:9]=1)[C:7]1[CH:10]=[C:11]([CH3:15])[C:12]([CH3:14])=[CH:13][C:6]=1[N:5]2[CH2:16][CH3:17].[CH2:18]=O.[CH2:20]([NH:22][CH2:23][CH3:24])[CH3:21]>C(O)C>[CH2:20]([N:22]([CH2:18][C:9]1[N:8]2[C:4]([N:5]([CH2:16][CH3:17])[C:6]3[CH:13]=[C:12]([CH3:14])[C:11]([CH3:15])=[CH:10][C:7]=32)=[N:3][C:2]=1[CH3:1])[CH2:23][CH3:24])[CH3:21]

Participants

5

Reactant 3

HCID 712FormaldehydeHCID 8021DiethylamineHCID 19040803HCID 19040803, compound

Product 1

HCID 19040835HCID 19040835, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

A solution of 1.5 g (6.5 mmol) of 2,6,7-trimethyl-9-ethylimidazo[1,2-a]benzimidazole in 8 ml of ethanol is mixed with 0.6 ml (7.5 mmol) of 40% formaldehyde and diethylamine (0.76 ml, 7.5 mmol). Stir at room temperature. Once the reaction is complete (verified by thin- layer chromatographiy), evaporate, wash the residue with water, dry, and recrystallise from petroleum ether.

Workup

  1. customevaporate
  2. washwash the residue with water
  3. customdry
  4. customrecrystallise from petroleum ether

Sources & evidence

ORD record
ord-2c63d209e18742298c502479ff6ed00e
Source dataset
uspto-grants-1997_06
Patent number
US05639756

Reaction notes

Loading…