1H-Pyrazole, 4-chloro- → HCID 19040645, compound

Participants

Reaction Steps

Using the general procedure of Example 11, replacing [(9-chloro-2,3,4,5-tetrahydro-3-methyl-1H-3-benzazepin-6-yl)oxy]ethanol 4-methylbenzenesulfonate with 6-chloro-9-(3-chloropropyl)-2,3,4,5-tetrahydro-3-methyl-1H-3-benzazepine and 1H-1,2,4-triazole sodium salt with 4-chloro-1H-pyrazole gave 0.33 g (60%) of 6-chloro-9-[3-(4-chloro-1H-pyrazol-1-yl)propyl]-2,3,4,5-tetrahydro-3-methyl-1H-3-benzazepine hydrochloride; mp 142.5°-145° C.

Provenance & Evidence