Water → HCID 19041522, compound

Participants

Reaction Steps

A solution of N-(4-amino-indan-2-yl)-N-propylpropionamide (0.5 g, 2.0 mmol) in dry diethyl ether (10 mL) was added to a slurry of lithium aluminum hydride (0.2 g, 5.4 mmol) in diethyl ether (50 mL) at ambient temperature. After stirring for 1.5 hours water (0.2 mL) followed by 15% sodium hydroxide (0.2 mL) and water (0.6 mL). After stirring for 10 minutes, the inorganic material was filtered off and the resulting solution was evaporated to yield 0.42 g (90%) of the desired product as an oil.:

Provenance & Evidence