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HRID1684016

反应详情

EQUATION

反应方程式

HRID 1684016 的结构方程式

REACTANTS

反应物

2
结构：COc1ccc(P2(=S)SP(=S)(c3ccc(OC)cc3)S2)cc1
HCID87949

p-Anisyldithiophosphonic anhydride

C14H14O2P2S4

结构：COc1ccc2c(c1)c(CC(C)CC(N)=O)c(C)n2Cc1ccc(Br)cc1
HCID19041650

未命名化合物

PRODUCTS

生成物

1
结构：COc1ccc2c(c1)c(CC(C)CC(N)=S)c(C)n2Cc1ccc(Br)cc1
HCID19041725

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：C1COCCO1
溶剂HCID31275

1,4-Dioxane

C4H8O2

PROCEDURE

实验过程

To the amide (530 mg, 1.30 mmol) of Example 90 in 1,4-dioxane (10.0 mL) was added the Lawesson reagent (310 mg, 0.767 mmol). After refluxing for 2 min, the solvent was evaporated in vacuo and the title product was purified by flash chromatography (30% EtOAc in hexane).

WORKUP

后处理

  1. temperatureAfter refluxing for 2 min
  2. customthe solvent was evaporated in vacuo
  3. customthe title product was purified by flash chromatography (30% EtOAc in hexane)