HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,6-Dimethylaniline → N-(2,6-dimethylphenyl)-2-methoxyacetamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,6-Dimethylaniline | HCID 6896 | — |
| Reactant | Methoxyacetic Acid | HCID 12251 | — |
| Product | N-(2,6-dimethylphenyl)-2-methoxyacetamide | HCID 10878014 | — |
Reaction Steps
According to the process described in the HU-PS 202,481, after acylating 2,6-dimethylaniline with methoxyacetic acid, the N-methoxyacetyl-2,6-dimethylaniline obtained is heated together with a twofold excess of methyl DL-α-bromopropionate to 120° C., and after adding sodium methoxide in small portions to the reaction mixture obtained, the alkylation is carried out at 140° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05639905 |
| Source dataset | uspto-grants-1997_06 |
| ORD ID | ord-174a8a78610640b18084f1c96cc4a474 |
| Source note | uspto-grants-1997_06 |