Ethanol → 1-O-tert-butyl 2-O-methyl 4-(4-ethenyl-1,3-dihydroisoindole-2-carbonyl)oxypyrrolidine-1,2-dicarboxylate

HRID 168429Notes

Reaction equation

HRID 168429 reaction equation
[Br:1][c:2]1[c:3]2[c:7]([cH:8][cH:9][cH:10]1)[CH2:6][N:5]([C:11](=[O:12])[O:13][CH:14]1[CH2:15][CH:16]([C:26](=[O:27])[O:28][CH3:29])[N:17]([C:19](=[O:20])[O:21][C:22]([CH3:23])([CH3:24])[CH3:25])[CH2:18]1)[CH2:4]2.[CH3:30][CH2:31][N:32]([CH2:33][CH3:34])[CH2:35][CH3:36].[CH3:37][CH2:38][OH:39].[K+:45].[S:40](=[O:41])(=[O:42])([OH:43])[O-:44]>>[c:2]1([CH:30]=[CH2:31])[c:3]2[c:7]([cH:8][cH:9][cH:10]1)[CH2:6][N:5]([C:11](=[O:12])[O:13][CH:14]1[CH2:15][CH:16]([C:26](=[O:27])[O:28][CH3:29])[N:17]([C:19](=[O:20])[O:21][C:22]([CH3:23])([CH3:24])[CH3:25])[CH2:18]1)[CH2:4]2

Participants

6

Reactant 5

HCID 702EthanolHCID 813Potassium CationHCID 8471TriethylamineHCID 61778Sulfate, hydrogenHCID 668881441-Tert-butyl 2-methyl 4-(4-bromoisoindoline-2-carbonyloxy)pyrrolidine-1,2-dicarboxylate

Product 1

HCID 668886711-O-tert-butyl 2-O-methyl 4-(4-ethenyl-1,3-dihydroisoindole-2-carbonyl)oxypyrrolidine-1,2-dicarboxylate

Sources & evidence

ORD record
ord-2bfeb89da0d54a62a7803876d3cdcbad
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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