HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 14697649, compound → HCID 19039457, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 14697649 | HCID 14697649 | — |
| Reactant | HCID 19039453 | HCID 19039453 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 19039457 | HCID 19039457 | 93.7% |
Reaction Steps
3-Amino-1-methyl-5-phenyl-2,3,4,5-tetrahydro-2,4-dioxo-1H-1,5-benzodiazepine (360 mg) was suspended in dry THF (10 ml) under nitrogen. N-(3-cyanophenyl)-1H-imidazole-1-carboxamide (326 mg) was added, and the mixture stirred at room temperature for 2 h. The mixture was filtered to give the title compound (510 mg) as a white solid m.p.>250°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05641775 |
| Source dataset | uspto-grants-1997_06 |
| ORD ID | ord-72b255aac3ce4621b159a51f352cbc80 |
| Source note | uspto-grants-1997_06 |