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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1684516Generated: October 30, 2026

HCID 14697649, compound → HCID 19039457, compound

https://huagongshe.com/reaction/1684516

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 14697649HCID 14697649—
ReactantHCID 19039453HCID 19039453—
SolventTetrahydrofuranHCID 8028—
ProductHCID 19039457HCID 1903945793.7%

Reaction Steps

3-Amino-1-methyl-5-phenyl-2,3,4,5-tetrahydro-2,4-dioxo-1H-1,5-benzodiazepine (360 mg) was suspended in dry THF (10 ml) under nitrogen. N-(3-cyanophenyl)-1H-imidazole-1-carboxamide (326 mg) was added, and the mixture stirred at room temperature for 2 h. The mixture was filtered to give the title compound (510 mg) as a white solid m.p.>250°.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05641775
Source datasetuspto-grants-1997_06
ORD IDord-72b255aac3ce4621b159a51f352cbc80
Source noteuspto-grants-1997_06