HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Triethylamine → Ethyl N-[chloro(4-chlorophenoxy)phosphoryl]-L-alaninate
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Triethylamine | HCID 8471 | — |
| Edukt | L-Alanine, ethyl ester, hydrochloride (1:1) | HCID 2724356 | — |
| Edukt | HCID 86761540 | HCID 86761540 | — |
| Lösungsmittel | Dichloromethane | HCID 6344 | — |
| Produkt | Ethyl N-[chloro(4-chlorophenoxy)phosphoryl]-L-alaninate | HCID 44226153 | — |
Reaktionsschritte
Following the procedure described for Step 1 of Example 1, treatment of a DCM (0.16 M) solution of para-chlorophenyl dichlorodiphosphate with L-alanine ethyl ester hydrochloride (1.0 eq.) and Et3N (2.0 eq.) provided the title compound as a colourless oil as a 1:1 mixture of diastereomers.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08148349B2 |
| Quelldatensatz | uspto-grants-2012_04 |
| ORD ID | ord-2cc961f870114721a1ce6b7f9bd72c62 |
| Quellennotiz | uspto-grants-2012_04 |