反应详情

1-Chloro-3-hydroxy-propan-2-one (15.06 g) and thiourea (8.36 g) were dissolved in EtOH (55 mL) and heated at reflux over 30 min. The reaction mixture was concentrated under reduced pressure to afford the desired product.

1. temperatureheated
2. temperatureat reflux over 30 min
3. concentrationThe reaction mixture was concentrated under reduced pressure