HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethanol → Acetic acid 2-amino-thiazol-4-ylmethyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethanol | HCID 702 | — |
| Reactant | 1-Chloro-3-hydroxy-2-propanone | HCID 90494 | — |
| Reactant | Thiourea | HCID 2723790 | — |
| Product | Acetic acid 2-amino-thiazol-4-ylmethyl ester | HCID 21915033 | — |
Reaction Steps
1-Chloro-3-hydroxy-propan-2-one (15.06 g) and thiourea (8.36 g) were dissolved in EtOH (55 mL) and heated at reflux over 30 min. The reaction mixture was concentrated under reduced pressure to afford the desired product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08148380B2 |
| Source dataset | uspto-grants-2012_04 |
| ORD ID | ord-fa3d1f2b4e6948d5999f82786c304316 |
| Source note | uspto-grants-2012_04 |