HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1685108Generated: October 31, 2026
Morpholine → 6-(Morpholin-4-yl)pyridin-2-amine
https://huagongshe.com/reaction/1685108
Participants
| Role | Name | HCID | Charge |
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| Reactant | Morpholine | HCID 8083 | — |
| Reactant | 2-Amino-6-chloropyridine | HCID 206246 | — |
| Product | 6-(Morpholin-4-yl)pyridin-2-amine | HCID 18771860 | — |
Reaction Steps
A mixture of 2-amino-6-chloropyridine in 100 mL of morpholine was heated at 225° C. for 60 mins. The mixture was cooled and precipitate filtered off, the filtrate was concentrated to give the 17 gram product as a brown oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US08148367B2 |
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| Source dataset | uspto-grants-2012_04 |
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| ORD ID | ord-5420d8f6d19e4bcf92b4bfd6b98332b2 |
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| Source note | uspto-grants-2012_04 |
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