HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → HCID 178429275, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Methyl acetoacetate | HCID 7757 | — |
| Reactant | 5-Amino-1H-pyrazol-3-ol | HCID 96221 | — |
| Solvent | Hydrochloric Acid | HCID 313 | — |
| Product | HCID 178429275 | HCID 178429275 | — |
Reaction Steps
20 g (201.8 mmol) of 5-amino-2H-pyrazol-3-ol and 26 g (224 mmol) of methyl 3-oxo-butyrate were heated under reflux in 63 ml of conc. hydrochloric acid and 17 ml of water for 1 h. After cooling, the product crystallized and was filtered off with suction and dried. Yield: 16.54 g (50%), M+H+: 166.07.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08148395B2 |
| Source dataset | uspto-grants-2012_04 |
| ORD ID | ord-cddf479efdec40a09138557cb50cfbfc |
| Source note | uspto-grants-2012_04 |