HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → 1-Butyl-6-chloro-4-methyl-3-oxo-1,3-dihydropyrazolo[3,4-b]pyridine-2-carboxylic acid hexylamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | Butyl iodide | HCID 10962 | — |
| Reactant | HCID 86628147 | HCID 86628147 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 1-Butyl-6-chloro-4-methyl-3-oxo-1,3-dihydropyrazolo[3,4-b]pyridine-2-carboxylic acid hexylamide | HCID 16747671 | — |
Reaction Steps
In analogy to example 2, 100 mg (0.32 mmol) of 6-chloro-4-methyl-3-oxo-1,3-dihydropyrazolo[3,4-b]pyridine-2-carboxylic acid hexylamide were reacted with 59.2 mg (0.32 mmol) of 1-iodobutane in DMF with triethylamine at RT. Yield: 23 mg (19%), M+H+: 367.27.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08148395B2 |
| Source dataset | uspto-grants-2012_04 |
| ORD ID | ord-982511f9a9704f4bb984d0027e8d37bc |
| Source note | uspto-grants-2012_04 |