Hexyl isocyanate → HCID 67265988, compound

HRID 1685236Notes

Reaction equation

HRID 1685236 reaction equation
[F:1][C:2]([F:14])([F:13])[C:3]1[N:8]=[C:7]2[O:9][N:10]=[C:11]([OH:12])[C:6]2=[CH:5][CH:4]=1.[N:15]([CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH3:23])=[C:16]=[O:17]>C1COCC1>[CH2:18]([NH:15][C:16]([N:10]1[C:11](=[O:12])[C:6]2[C:7](=[N:8][C:3]([C:2]([F:13])([F:1])[F:14])=[CH:4][CH:5]=2)[O:9]1)=[O:17])[CH2:19][CH2:20][CH2:21][CH2:22][CH3:23]

Participants

4

Reactant 2

HCID 75659Hexyl isocyanateHCID 178518994HCID 178518994, compound

Product 1

HCID 67265988HCID 67265988, compound

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

In analogy to example 1c, 47 mg (0.23 mmol) of 6-trifluoromethylisoxazolo-[5,4-b]pyridin-3-ol were reacted with 34.9 mg (0.27 mmol) of 1-isocyanatohexan in THF. Yield: 15 mg (20%), M+H+: 332.2.

Sources & evidence

ORD record
ord-c49bec9d04ed4bc9a77090b1d96b5333
Source dataset
uspto-grants-2012_04
Patent number
US08148395B2

Reaction notes

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