Hexyl isocyanate → HCID 67266031, compound

HRID 1685237Notes

Reaction equation

HRID 1685237 reaction equation
[CH3:1][C:2]1[N:7]=[C:6]2[O:8][N:9]=[C:10]([OH:11])[C:5]2=[CH:4][CH:3]=1.[N:12]([CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH3:20])=[C:13]=[O:14]>C1COCC1>[CH2:15]([NH:12][C:13]([N:9]1[C:10](=[O:11])[C:5]2[C:6](=[N:7][C:2]([CH3:1])=[CH:3][CH:4]=2)[O:8]1)=[O:14])[CH2:16][CH2:17][CH2:18][CH2:19][CH3:20]

Participants

4

Reactant 2

HCID 75659Hexyl isocyanateHCID 178422985HCID 178422985, compound

Product 1

HCID 67266031HCID 67266031, compound

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

In analogy to example 1c, 50 mg (0.33 mmol) of 6-methylisoxazolo[5,4-b]pyridin-3-ol were reacted with 50.8 mg (0.4 mmol) of 1-isocyanatohexane in THF. Yield: 30 mg (32%), M+H+: 278.1.

Sources & evidence

ORD record
ord-47bdcc7bc4774fbbbde04f6483777447
Source dataset
uspto-grants-2012_04
Patent number
US08148395B2

Reaction notes

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