Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 168524Generated: October 30, 2026

Diethyl Ether → 3-(2,3-Dimethoxy-pyridin-4-yl)-3-hydroxy-pentanoic acid tert-butyl ester

https://huagongshe.com/reaction/168524

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDiethyl EtherHCID 3283—
ReactantChlorotrimethylsilaneHCID 6397—
ReactantTetrahydrofuranHCID 8028—
ReactantZincHCID 23994—
Reactanttert-Butyl bromoacetateHCID 79177—
Reactant1-(2,3-Dimethoxy-pyridin-4-yl)-propan-1-oneHCID 59217942—
Product3-(2,3-Dimethoxy-pyridin-4-yl)-3-hydroxy-pentanoic acid tert-butyl esterHCID 59217931—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (9/10)
ORD IDord-4505bb2bcbf949e98ac7ef8fe6033509
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (9/10)