Diethyl Ether → 3-(2,3-Dimethoxy-pyridin-4-yl)-3-hydroxy-pentanoic acid tert-butyl ester
Reaction equation
[C:6]([CH3:7])([CH3:8])([CH3:9])[O:10][C:11]([CH2:12][Br:13])=[O:14].[CH3:15][O:16][c:17]1[n:18][cH:19][cH:20][c:21]([C:25]([CH2:26][CH3:27])=[O:28])[c:22]1[O:23][CH3:24].[CH3:1][Si:2]([Cl:3])([CH3:4])[CH3:5].[CH3:29][CH2:30][O:31][CH2:32][CH3:33].[O:34]1[CH2:35][CH2:36][CH2:37][CH2:38]1.[Zn:39]>>[C:6]([CH3:7])([CH3:8])([CH3:9])[O:10][C:11]([CH2:12][C:25]([c:21]1[cH:20][cH:19][n:18][c:17]([O:16][CH3:15])[c:22]1[O:23][CH3:24])([CH2:26][CH3:27])[OH:28])=[O:14]Participants
7
Sources & evidence
- ORD record
- ord-4505bb2bcbf949e98ac7ef8fe6033509
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
Loading…