1H-Pyrrolo(2,3-b)pyridine → HCID 10220373, compound

HRID 1685243Notes

Reaction equation

HRID 1685243 reaction equation
[NH:1]1[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][N:8]=2)[CH:3]=[CH:2]1.[NH:10]1[CH2:14][CH2:13][CH2:12][CH2:11]1>C(O)C>[CH2:13]1[CH:14]2[N:10]([CH2:2][CH:3]=[C:4]([C:3]3[C:4]4[C:9](=[N:8][CH:7]=[CH:6][CH:5]=4)[NH:1][CH:2]=3)[CH2:5]2)[CH2:11][CH2:12]1

Participants

4

Reactant 2

HCID 92221H-Pyrrolo(2,3-b)pyridineHCID 31268Pyrrolidine

Product 1

HCID 10220373HCID 10220373, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

from 7-azaindole (500 mg, 4.2 mmol), 1,2,3,5,6,8,8a-heptahydrohydro-7-oxo-indolizine (589 mg, 4.2 mmol) and pyrrolidine (3.0 g, 42 mmol) in ethanol (4 mL) heating at reflux for 5 hrs.

Workup

  1. temperatureat reflux for 5 hrs

Sources & evidence

ORD record
ord-0fed0caedb194e5dba14ffae504b41af
Source dataset
uspto-grants-2012_04
Patent number
US08148394B2

Reaction notes

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