反应详情

The title material was prepared according to the general procedure outlined for the synthesis of (S)-2-amino-1-[3-chloro-4-methoxyphenyl]ethanol hydrochloride. LRMS [M+H]+ 217.9; IR (KBr, cm−1) 3025, 3443, 2891; 1H NMR (500 MHz, DMSO-d6) δ 7.93 (b s, 2H), 7.60 (s, 1H), 7.52 (d, 1H), 7.41 (s, 1H), 7.35 (d, J=7.7 Hz, 1H) 6.17 (s, 1H), 4.82 (m, 1H), 3.08 (ddd, J=2.6, 12.7, 9.6 Hz, 2H); 13C NMR (DMSO-d6, 75.5 MHz) δ 144.4, 130.5, 128.7, 125.0, 121.6, 68.3, 45.1.