Trifluoroacetic acid → HCID 59200381, compound

HRID 1685322Notes

Reaction equation

HRID 1685322 reaction equation
[CH2:1]([NH:6][CH2:7][C:8]([C:24]1[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=1)([C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1)[CH2:9][NH:10]C(=O)OC(C)(C)C)[C:2]([CH3:5])([CH3:4])[CH3:3].FC(F)(F)C(O)=O>ClCCl>[CH2:1]([NH:6][CH2:7][C:8]([C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1)([C:24]1[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=1)[CH2:9][NH2:10])[C:2]([CH3:5])([CH3:4])[CH3:3]

Participants

4

Reactant 2

HCID 6422Trifluoroacetic acidHCID 67266052HCID 67266052, compound

Product 1

HCID 59200381HCID 59200381, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

The title material was prepared by treating a solution of the crude tert-butyl 3-(neopentylamino)-2,2-diphenylpropylcarbamate (0.055 g) in dichloromethane (5 mL) with trifluoroacetic acid (1 mL) at 23° C. for 30 minutes. The reaction was concentrated to dryness and the residue was used as such in the next reaction.

Workup

  1. concentrationThe reaction was concentrated to dryness
  2. customsuch in the next reaction

Sources & evidence

ORD record
ord-c61c9d3128a24100bc6d251d548273ad
Source dataset
uspto-grants-2012_04
Patent number
US08148400B2

Reaction notes

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