Trifluoroacetic acid → HCID 350082, compound

HRID 1685324Notes

Reaction equation

HRID 1685324 reaction equation
[C:1]1([C:7]([C:24]2[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=2)([CH2:17][N:18]2[CH2:23][CH2:22][CH2:21][CH2:20][CH2:19]2)[CH2:8][NH:9]C(=O)OC(C)(C)C)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.FC(F)(F)C(O)=O>ClCCl>[C:1]1([C:7]([C:24]2[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=2)([CH2:17][N:18]2[CH2:23][CH2:22][CH2:21][CH2:20][CH2:19]2)[CH2:8][NH2:9])[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1

Participants

4

Reactant 2

HCID 6422Trifluoroacetic acidHCID 67266161HCID 67266161, compound

Product 1

HCID 350082HCID 350082, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

The title material was obtained by treating a solution of tert-butyl 2,2-diphenyl-3-(piperidin-1-yl)propylcarbamate (0.109 g) in dichloromethane (5 mL) with trifluoroacetic acid (1 mL) at 23° C. for 45 minutes. The reaction was then concentrated to dryness and the residue was used as such in the next reaction.

Workup

  1. concentrationThe reaction was then concentrated to dryness
  2. customsuch in the next reaction

Sources & evidence

ORD record
ord-41a40930db9d4a79a5c7dc7670998b4b
Source dataset
uspto-grants-2012_04
Patent number
US08148400B2

Reaction notes

Loading…