(4-Methoxyphenyl)boronic acid → HCID 67292542, compound

HRID 1685433Notes

Reaction equation

HRID 1685433 reaction equation
[C:1]([O:4][C@@H:5]1[C@@H:18]([O:19][C:20](=[O:22])[CH3:21])[C@H:17]([O:23][C:24](=[O:26])[CH3:25])[CH2:16][S:15][C@H:6]1[O:7][C:8]1[CH:13]=[CH:12][N:11]=[C:10](Br)[CH:9]=1)(=[O:3])[CH3:2].[CH3:27][O:28][C:29]1[CH:34]=[CH:33][C:32](B(O)O)=[CH:31][CH:30]=1>>[C:1]([O:4][C@@H:5]1[C@@H:18]([O:19][C:20](=[O:22])[CH3:21])[C@H:17]([O:23][C:24](=[O:26])[CH3:25])[CH2:16][S:15][C@H:6]1[O:7][C:8]1[CH:13]=[CH:12][N:11]=[C:10]([C:32]2[CH:33]=[CH:34][C:29]([O:28][CH3:27])=[CH:30][CH:31]=2)[CH:9]=1)(=[O:3])[CH3:2]

Participants

3

Reactant 2

HCID 201262(4-Methoxyphenyl)boronic acidHCID 86625028HCID 86625028, compound

Product 1

HCID 67292542HCID 67292542, compound

Procedure

By following a procedure analogous to Example 27 starting from the 2-bromo-4-pyridinyl 2,3,4-tri-O-acetyl-5-thio-β-D-xylopyranoside obtained according to Preparation 25 and 4-methoxyphenylboronic acid, 2-(4-methoxyphenyl)-4-pyridinyl 2,3,4-tri-O-acetyl-5-thio-β-D-xylopyranoside is obtained in the form of a beige solid (yield=53%).

Workup

  1. customobtained

Sources & evidence

ORD record
ord-901b25ce6fbf4c25a2fbdf778cee562b
Source dataset
uspto-grants-2012_04
Patent number
US08148407B2

Reaction notes

Loading…