2-Aminothiazole → HCID 52901039, compound

HRID 1685559Notes

Reaction equation

[CH3:1][N:2]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[C:4]([C:11]([OH:13])=O)=[CH:3]1.[NH2:14][C:15]1[S:16][CH:17]=[CH:18][N:19]=1>>[S:16]1[CH:17]=[CH:18][N:19]=[C:15]1[NH:14][C:11]([C:4]1[C:5]2[C:10](=[CH:9][CH:8]=[CH:7][CH:6]=2)[N:2]([CH3:1])[CH:3]=1)=[O:13]

Participants

Reactant 2

HCID 21552-Aminothiazole

HCID 8540401-Methylindole-3-carboxylic acid

Product 1

HCID 52901039HCID 52901039, compound

Procedure

1-Methyl-1H-indole-3-carboxylic acid and 2-aminothiazole was coupled and purified according to the conditions described in General Procedure (B), Step C).

Workup

custompurified

Sources & evidence

ORD record: ord-4a6724f65ffe4df5872653039d5f5b2c
Source dataset: uspto-grants-2012_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08148413B2

Reaction notes

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