2-Amino-5-methylthiazole → HCID 59513992, compound
Reaction equation
[S:1]1[CH:5]=[CH:4][N:3]=[C:2]1[NH:6][C:7]([C:9]1[C:17]2[C:12](=[CH:13][C:14]([CH2:18][OH:19])=[CH:15][CH:16]=2)[N:11]([CH2:20][CH:21]2[CH2:23][CH2:22]2)[CH:10]=1)=[O:8].N[C:25]1SC(C)=CN=1>>[CH3:25][C:5]1[S:1][C:2]([NH:6][C:7]([C:9]2[C:17]3[C:12](=[CH:13][C:14]([CH2:18][OH:19])=[CH:15][CH:16]=3)[N:11]([CH2:20][CH:21]3[CH2:23][CH2:22]3)[CH:10]=2)=[O:8])=[N:3][CH:4]=1Participants
3
Procedure
The compound was prepared according to the procedure given for 1-Cyclopropylmethyl-6-hydroxymethyl-1H-indole-3-carboxylic acid thiazol-2-ylamide using 2-amino-5-methyl-thiazole.
Workup
- customThe compound was prepared
Sources & evidence
- ORD record
- ord-3b2e9f9b1ec249f996c6590eea627da4
- Source dataset
- uspto-grants-2012_04
- Patent number
- US08148413B2
Reaction notes
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