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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1685598Generated: November 2, 2026

Iodoethane → 4778-76-1

https://huagongshe.com/reaction/1685598

Reaction equation

Participants

RoleNameHCIDCharge
ReactantIodoethaneHCID 6340—
Reactant4-Thiazoleacetic acid, 2-amino-, ethyl esterHCID 104454—
ReactantEthyl 1H-pyrrole-2-carboxylateHCID 255670—
Reactant4778-76-1HCID 15442598—
Product4778-76-1HCID 15442598—
ProductHCID 43638978HCID 43638978—

Reaction Steps

1-Ethylpyrrole-2-carboxylic acid (90 mg) was prepared from ethyl-pyrrole-2-carboxylate (140 mg, 1.0 mmol) and ethyl iodide (0.12 mL, 1.5 mmol) following the general procedures A and B. (2-{[1-Ethylpyrrole-2-carbonyl]-amino}-thiazol-4-yl)acetic acid ethyl ester (46 mg) was prepared from 1-ethylpyrrole-2-carboxylic acid (90 mg, 0.53 mmol) and 2-aminothiazol-4-yl acetic acid ethyl ester (95 mg, 0.53 mmol) following the general procedure F.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08148413B2
Source datasetuspto-grants-2012_04
ORD IDord-e8b8d30bc6cc4bb6b00aff444735e4e7
Source noteuspto-grants-2012_04