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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1686002Generated: November 1, 2026

Trifluoroacetic acid → HCID 57699902, compound

https://huagongshe.com/reaction/1686002

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
ReactantHCID 67265368HCID 67265368—
SolventDichloromethaneHCID 6344—
ProductHCID 57699902HCID 57699902111.9%

Reaction Steps

To a solution of (S)-4-[4-(4-benzoylamino-phenoxy)-6-methoxy-quinolin-7-yloxy]-2-tert-butylcarbonylamino-butyric acid (6.5 mg, 0.011 mmol) in DCM (1 ml) was added TFA (1 ml). The reaction was allowed to stir for 6 hours and then evaporated under reduced pressure to afford the title compound as an off-white solid (6.0 mg, 90% yield).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08148531B2
Source datasetuspto-grants-2012_04
ORD IDord-e806d84fe4fe4df78fb821412ceade0e
Source noteuspto-grants-2012_04