HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → HCID 57699902, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | HCID 67265368 | HCID 67265368 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 57699902 | HCID 57699902 | 111.9% |
Reaction Steps
To a solution of (S)-4-[4-(4-benzoylamino-phenoxy)-6-methoxy-quinolin-7-yloxy]-2-tert-butylcarbonylamino-butyric acid (6.5 mg, 0.011 mmol) in DCM (1 ml) was added TFA (1 ml). The reaction was allowed to stir for 6 hours and then evaporated under reduced pressure to afford the title compound as an off-white solid (6.0 mg, 90% yield).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08148531B2 |
| Source dataset | uspto-grants-2012_04 |
| ORD ID | ord-e806d84fe4fe4df78fb821412ceade0e |
| Source note | uspto-grants-2012_04 |