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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1686387Generated: October 26, 2026

1,2-Difluoro-4-(methylsulfonyl)benzene → {4-Chloro-3-[2-fluoro-4-(methylsulfonyl)phenoxy]phenyl}acetic acid

https://huagongshe.com/reaction/1686387

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,2-Difluoro-4-(methylsulfonyl)benzeneHCID 2782743—
Reactant4-Chloro-3-hydroxyphenylacetic acidHCID 3017183—
Product{4-Chloro-3-[2-fluoro-4-(methylsulfonyl)phenoxy]phenyl}acetic acidHCID 57791958—

Reaction Steps

The title compound was prepared by the method of example 2 step (iii) using 3,4-difluorophenyl methyl sulfone and the product of example 1 step (iii).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08148572B2
Source datasetuspto-grants-2012_04
ORD IDord-54404c4e07054a6cb517702f8e4f89d9
Source noteuspto-grants-2012_04