HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzene → (3-Chloro-4-fluorophenyl)(phenyl)methanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzene | HCID 241 | — |
| Reactant | 3-Chloro-4-fluorobenzoyl Chloride | HCID 2736548 | — |
| Solvent | Water | HCID 962 | — |
| Product | (3-Chloro-4-fluorophenyl)(phenyl)methanone | HCID 15023215 | — |
Reaction Steps
3-chloro-4-fluorobenzoyl chloride (1.0 g), benzene (2 ml) and ferric chloride (0.28 g) were heated to reflux for 16 h then diluted with water, extracted with ethyl acetate and the organics dried (MgSO4) and evaporated under reduced pressure to give the subtitle compound as a brown solid (0.8 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08148572B2 |
| Source dataset | uspto-grants-2012_04 |
| ORD ID | ord-eea1459a686f4bd9aac3986c2d36801b |
| Source note | uspto-grants-2012_04 |