Potassium Cation → 6-Methoxy-7-(3-morpholinopropoxy)-3-pivaloyloxymethyl-3,4-dihydroquinazolin-4-one

HRID 168673Notes

Reaction equation

HRID 168673 reaction equation
[C:1](=[O:2])([O-:3])[O-:4].[CH3:39][N:40]([CH3:41])[CH:42]=[O:43].[K+:5].[K+:6].[O:29]1[CH2:30][CH2:31][N:32]([CH2:35][CH2:36][CH2:37][Cl:38])[CH2:33][CH2:34]1.[OH:7][c:8]1[c:9]([O:27][CH3:28])[cH:10][c:11]2[c:12](=[O:26])[n:13]([CH2:18][O:19][C:20]([C:21]([CH3:22])([CH3:23])[CH3:24])=[O:25])[cH:14][n:15][c:16]2[cH:17]1>>[O:7]([c:8]1[c:9]([O:27][CH3:28])[cH:10][c:11]2[c:12](=[O:26])[n:13]([CH2:18][O:19][C:20]([C:21]([CH3:22])([CH3:23])[CH3:24])=[O:25])[cH:14][n:15][c:16]2[cH:17]1)[CH2:37][CH2:36][CH2:35][N:32]1[CH2:31][CH2:30][O:29][CH2:34][CH2:33]1

Participants

6

Reactant 5

HCID 813Potassium Cation2×HCID 6228DimethylformamideHCID 19660Carbonate IonHCID 958344-(3-Chloropropyl)morpholineHCID 10804576(7-Hydroxy-6-methoxy-4-oxoquinazolin-3(4H)-yl)methyl pivalate

Product 1

HCID 227322766-Methoxy-7-(3-morpholinopropoxy)-3-pivaloyloxymethyl-3,4-dihydroquinazolin-4-one

Sources & evidence

ORD record
ord-351dfbb3551142abbb2cc029cdc41bd0
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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