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HRID1687593

反应详情

EQUATION

反应方程式

HRID 1687593 的结构方程式

REACTANTS

反应物

4
结构：CC(=O)O
HCID176

Acetic Acid

C2H4O2

结构：CC(=O)OC(C)=O
HCID7918

Acetic anhydride

C4H6O3

结构：C1CCOC1
HCID8028

Tetrahydrofuran

C4H8O

结构：CNC(=O)c1ccc(N)cc1Nc1nc(Cl)ncc1Cl
HCID86633983

未命名化合物

PRODUCTS

生成物

1
结构：CNC(=O)c1ccc(NC(C)=O)cc1Nc1nc(Cl)ncc1Cl
HCID86633984

未命名化合物

PROCEDURE

实验过程

4-Amino-2-(2,5-dichloro-pyrimidin-4-ylamino)-N-methyl-benzamide (0.135 g, 0.000432 mol), Acetic anhydride (0.0428 mL, 0.000454 mol), THF (5 mL, 0.06 mol) and Acetic acid (0.024 mL, 0.43 mol) were stirred at rt for 16 h. Product isolated as white ppt (80 mg, 52%).

WORKUP

后处理

  1. customProduct isolated as white ppt (80 mg, 52%)